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How Cancers Evolve Drug Resistance


Receiving three separate courses of a new class of anticancer immunotherapy agents is not typical for a cancer patient, yet that is what retired Major League Baseball administrator Bill Murray, now 79, endured to treat his melanoma. “When I was told that I might be dying from melanoma, I thought... Read More

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CRISPR Can Track Cellular History of a Mammalian Embryo- Researchers used the genome-editing technology to analyze the development of mouse tissues.


Using CRISPR, researchers have crafted a technique to study mammalian development in exceptional detail, according to a report published in Science yesterday (August 9).“This method allows us to take the final developmental stage of a model organism and from there reconstruct a full li... Read More

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Tracking the Evolutionary History of a Tumor - Analyzing single cell sequences to decipher the evolution of a tumor


By the time a person arrives at the doctor’s office with a tumor, a lot has already happened at the cellular-and genomic-level. That cancer sprang from one mutant cell that spawned a mass of cells with additional nucleotide changes and diverse phenotypes.To understand the evolutionary history o... Read More

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